As the race for European football heats up in the Premier League, hopefuls Bournemouth will welcome relegation-threatened Ipswich Town to the Vitality Stadium on Wednesday.
The Cherries will be looking to get back on track after a difficult March, while the Tractor Boys will be desperate to end their five-game losing streak.
We say: Bournemouth 2-1 Ipswich Town
Both sides have been in poor form in the weeks leading up to this clash, but they each have their own clear goals for the remainder of the campaign and will have used the international break to reset.
However, Bournemouth have proven themselves to be extremely capable under Iraola, and if they can get recapture their early-season form, expect them to take all three points on Wednesday.
> Premier League preview: Bournemouth vs Ipswich
> Can Ipswich survive with six out? Who starts for McKenna against Bournemouth?
> Back after four months out: Who could Iraola start in chase for Europe?
The battle for European qualification will continue on Wednesday night as Brighton & Hove Albion welcome Aston Villa to the American Express Stadium for a Premier League clash.
The hosts are reeling from a penalty shootout defeat in the FA Cup quarter-finals over the weekend, while the visitors will be buoyed by securing their place at Wembley for the semi-finals.
We say: Brighton & Hove Albion 1-1 Aston Villa
As both teams are battling for crucial points in the battle for a Champions League finish, this match is likely to be an extremely hard-fought affair.
Although Aston Villa have a strong record against Brighton, the hosts have been solid at home while the visitors have often struggled on the road, leading us to expect a draw.
> Premier League preview: Brighton vs Aston Villa
> How Aston Villa could line up against Brighton & Hove Albion
> How Brighton & Hove Albion could line up against Aston Villa
Looking to boost their chances of a Champions League finish, Manchester City will welcome Championship-bound Leicester City to the Etihad on Wednesday night for a Premier League clash.
The Citizens booked their customary spot in the semi-finals of the FA Cup over the weekend, whereas the Foxes have been afforded two weeks to mull over yet another disappointing defeat in the top flight.
We say: Manchester City 2-0 Leicester City
Despite their stuttering form at the Etihad in recent times, Manchester City should be supremely confident of easing past the attentions of relegation-threatened Leicester.
The faltering Foxes are aiming to avoid their eighth straight defeat across all competitions, with Wednesday night set to be another sobering occasion for the East Midlands outfit.
> Premier League preview: Man City vs Leicester
> Solving an attacking crisis: Leicester predicted XI vs. Man City
> Will Haaland play a part? Man City predicted XI vs. Leicester
> Haaland, Rodri, Bobb latest: Man City injury list for Leicester clash
EFL Cup champions Newcastle United continue their quest for Champions League football when they host Brentford at St James’ Park in the Premier League on Wednesday.
The Magpies are in sixth place with 47 points and are only two points from fourth-placed Chelsea, while the Bees are in 11th place with 41 points and beat Bournemouth 2-1 on March 15 in their last league outing.
We say: Newcastle United 1-2 Brentford
Brentford are excellent duellists and will be able to match Newcastle’s physicality across the pitch.
Additionally, the Bees’ counter-attacking threat away from home has been excellent in recent weeks, and they could win at St James’ Park on Wednesday.
> Premier League preview: Newcastle vs Brentford
> Who will support Isak? How Howe could line up Magpies against Brentford on Wednesday
After securing their place in the FA Cup semi-finals, Crystal Palace will turn their focus back to Premier League action for Wednesday’s meeting with Southampton at St Mary’s.
Palace are sitting in 12th place with 39 points to their name, while the Saints are languishing at the bottom of the table with just nine points from 29 matches.
We say: Southampton 1-3 Crystal Palace
In contrast to Southampton, Palace will be full of confidence after winning each of their last five competitive matches, and we think the Eagles will continue to build momentum by claiming a relatively comfortable victory over a side that have lost their previous nine Premier League home games.
> Premier League preview: Southampton vs Crystal Palace
> Will Glasner make any changes? Predicted Crystal Palace XI vs. Southampton
> Will Bednarek, Harwood-Bellis be fit? Predicted Southampton XI vs. Crystal Palace
Liverpool and Everton lock horns in the Merseyside derby for the second time in two months when the two long-standing rivals go head-to-head at Anfield in the Premier League on Wednesday night.
James Tarkowski’s staggering 98th-minute equaliser for Everton at Goodison Park in February bid the Grand Old Lady a fond derby farewell, but that result has done little in the grand scheme of things to knock Liverpool off course in their quest for the title.
We say: Liverpool 2-0 Everton
The international break came at the perfect time for a Liverpool side whose season was threatening to tail off after seeing their hopes for two major honours fall by the wayside, and Slot has since had two weeks to reset and get his players back on track.
Everton’s record at Anfield in the 21st century is among the worst any club has suffered against another in Premier League history, with their solitary win coming behind closed doors in 2021, and an eighth straight defeat in front of a crowd is likely, despite their current nine-game unbeaten streak.
> Premier League preview: Liverpool vs Everton
> Problems mounting at right-back: Predicted Liverpool lineup vs. Everton
> Ndiaye, McNeil back in training: Predicted Everton lineup vs. Liverpool
> Alisson, Gravenberch latest: Liverpool injury, suspension list for Merseyside derby
